Huaier relieves oxaliplatin-induced hepatotoxicity through activation of the PI3K/AKT/Nrf2 signaling pathway in C57BL/6 mice
Hepatotoxicity caused by the anticancer medication oxaliplatin (OXA) significantly restricts its clinical use and raises the risk of liver damage.Huaier, a fungus found in China, has been demonstrated to have various beneficial effects in adjuvant therapy for cancer.However, the preventive impact of Huaier against OXA-induced hepatotoxicity is stil